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Drug-Induced Nutrient Depletions

People taking prescription drugs may be more likely to have reduced levels of certain nutrients. Drug-induced nutrient depletion occurs when the medications you take for your chronic health condition block the absorption, storage, metabolism, or synthesis of essential nutrients in the body. When nutrients are blocked or depleted over time, health problems can develop. Here are some examples of common drug-induced nutrient depletions.

Diabetes Medication

Nutrients Depleted

Short-Term Effects

Long-Term Effects

Sulfonylureas & 2nd Generation:

Glimepiride, Glipizide, Glyburide, Others:

Metformin, Acarbose,

Combos: Glucovance, Janumet


B2, B6, B12, CoQ10, Folic Acid, Magnesium,

Chromium, C, Zinc

Chronic Diarrhea, Fatigue/

Decreased Energy, Brain Fog,

Muscle Aches, Frequent Infections, Nausea, Decreased Immune Response

Decreased Libido, Memory Loss, Depression, Increased Risk of Heart Disease, Neuropathy, Vision Problems

High Blood Pressure Medication

Nutrients Depleted

Short-Term Effects

Long-Term Effects

Betablockers: Atenolol, Bisoprolol, Carvedilol,

Labetalol, Metoprolol, Propranolol,

Sotalol, Ace-Inhibitors & ARBS:

Benazepril, Enalapril, Lisinopril, Ramipril,

Diuretics: Furosemide, HCTZ, Triamterene,

Cardiac Glycosides: Lanoxin

CoQ10, Zinc, B1, B5, B6, B12, Magnesium, Folic

Acid, D, Potassium

Decreased Energy/Fatigue,

Drowsiness, Brain Fog, Leg Cramps, Easy Bruising, Decreased Immune Response

Memory Loss, Liver Damage,

Slow Wound Healing, Decreased Sex Drive

Cholesterol Medication

Nutrients Depleted

Short-Term Effects

Long-Term Effects

Statins: Atorvastatin, Simvastatin,

Lovastatin, Pravastatin, Rosuvastatin

Others: Gemfibrozil, Ezetimibe (Zeta),

Fenofibrate (Tricor), Cholestipol (Colestid),

Cholestyramine (Questran)

CoQ10, Magnesium,

E, B6, B12

Muscle Aches, Decreased Energy/

Fatigue, Brain Fog, Nausea, Anemia, Dry Skin/Hair, Easy


Vision Problems, Cardiovascular

Disease, Congestive Heart

Failure, Memory Loss, Liver Damage

Birth Control or Hormone Medication

Nutrients Depleted

Short-Term Effects

Long-Term Effects

All Oral Contraception/Birth Control Pills,

Premarin, PremPro, Estratab, Estrace,

Estradiol, and other Estrogen Derivatives

and selective Estrogen Receptor


Magnesium, Zinc, Folic Acid, C, B6, B2, B12

Decreased Energy/Fatigue,

Depression, Appetite Loss,

Anemia, Nausea, Anxiety

Decreased Libido,

Cardiovascular Disease,

Decreased Sleep

Proton Pump Inhibitor Medication

Nutrients Depleted

Short-Term Effects

Long-Term Effects

Omeprazole (Prilosec), Esomeprazole

(Nexium), Lansoprazole (Prevacid), Rabeprazole

(AcipHex), Pantoprazole (Protonix)

B12, D, Magnesium

Decreased Energy, Hair Loss,

Brittle Nails

Decreased Immune System

If you take any of these medications, our pharmacists recommend SolutionsRx Prescription Support. Prescription Support is a multivitamin and enzyme

combination specifically formulated to help maintain overall health and eliminate side effects as a result of drug-induced nutrient depletion. Recommended dosing is two capsules daily ($1/day).

If you are struggling to take your medication as directed due to side effects or other issues, please don’t hesitate to give us a call or stop by. We are here to support you on your journey to optimal health. Our experts have the knowledge and tools to help with all your medication questions and concerns.

*These statements are culmination of the knowledge and experience of the team at Norland Pharmacy. The information provided here is for informational purposes only. Please consult your healthcare provider with questions concerning any medical condition or treatment. Compounded medications are not reviewed by the FDA for safety or efficacy. These statements have not been evaluated by the Food and Drug Administration, and this product is not intended to diagnose, treat, cure or prevent any disease.


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